One characteristic linking members of the synaptotagmin family to endocytosis is their ability to bind the heterotetrameric AP2 complex via their C2B domain. By using CD4/synaptotagmin 1 chimeras, we ...

To allow substances such as neurotransmitters, nutrients, and even viruses to enter our cells, they are enclosed in vesicles at the cell membrane and transported into the cell interior. This transport ...

The assembly polypeptide 2 (AP2) complex is a key player in clathrin-mediated endocytosis (CME); it recruits clathrin to membranes, promotes the polymerization of clathrin into clathrin-coated pits ...

Malaria remains a significant threat to human health with approximately 216 million cases annually and over 400,000 deaths worldwide. It is caused by the Plasmodium parasite, which has a complex ...