Researchers have discovered an unusual case where two well-known cancer-related mutations—APC and KRAS—coexisted in a woman with familial adenomatous polyposis (FAP) and a history of endometrial ...
Familial adenomatous polyposis (FAP) is caused by mutations in the APC gene and 2 different, or biallelic mutations, in the MUTYH gene. However, not all patients with colorectal polyposis are found to ...
Researchers have discovered an unusual case where two well-known cancer-related mutations-APC and KRAS-coexisted in a woman with familial adenomatous polyposis (FAP) and a history of endometrial ...
Total neoadjuvant therapy with FOLFOX plus bevacizumab and short-course radiotherapy for Ras mutant, high-risk, locally advanced rectal cancer: The TRAINER trial. Phase Ib study of gevokizumab (GEVO) ...
Researchers from Japan report that they have characterized gene mutations in colorectal cancer (CRC) tumors with high tumor mutation burden that lack mutations in the major oncogenes. Their findings ...
Colorectal cancer (CRC), a type of cancer that affects the large intestine and rectum, is one of the leading causes of cancer-related deaths worldwide. The mutational landscape of CRC is ...
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