Scientists are racing to redesign how powerful painkillers work, aiming to keep the relief that opioids provide while ...

Researchers at USF Health have discovered a new way opioid receptors can work that may lead to safer pain medications. Their findings show that certain experimental compounds can amplify pain relief ...

New research reveals previously unknown ways opioid receptors can function, opening the door to safer pain treatments.

For decades, opioids have been the blunt instrument of modern pain care, powerful enough to quiet severe suffering yet risky ...

Experiments reveal that a time-dependent epistatic interaction influences how mice respond to opioids, and that intracellular fibroblast growth factors also influence opioid sensitivity.

Morphine is an opiate found in opium, the juice secreted by the seedpods of poppies. It is a potent pain reliever and is similar in structure to other opiate analgesics. As morphine binds to opioid ...

Analgesics are medications that relieve pain. They work either by reducing inflammation or by changing the way the brain processes and perceives pain. Side effects include heartburn, nausea, and ...

Koumine, a prominent monoterpene indole alkaloid isolated from Gelsemium elegans, has emerged as a compound of considerable interest due to its multifaceted pharmacological profile. Extensive ...

Opioids are a class of drugs prescribed for pain relief and sedation. Taking opioids long term may increase the risk of anxiety and depression as side effects. Opioids can cause many side effects, ...