This Review discusses the theory and practices behind the generation of combinatorial antibody libraries. Such libraries give scientists unprecedented control over the antibody repertoire. They have ...

Ten years ago, Stuart L. Schreiber of Harvard University and coworkers reported a technique for making natural-product-like compound collections that featured an unprecedented diversity of structures.

A framework based on advanced AI techniques can solve complex, computationally intensive problems faster and in a more more scalable way than state-of-the-art methods, according to a new study. A ...

Not so long ago, received wisdom in the psychology of trading and investing in financial markets said that the key to success was consistency. Once you found your probabilistic “edge” in markets, you ...

Conventional quantum algorithms are not feasible for solving combinatorial optimization problems (COPs) with constraints in the operation time of quantum computers. To address this issue, researchers ...

Using combinatorial chemistry, researchers have designed a new class of metallic glasses that works well at high temperatures and should be easy to form into useful components (Nature 2019, DOI: ...

In this graduate-level course, we will be covering advanced topics in combinatorial optimization. We will start with matchings and cover many results, extending the fundamental results of matchings, ...

Functional RNA Studies Are a Useful Tool in Variant Classification but Must Be Used With Caution: A Case Study of One BRCA2 Variant To improve the design of such ...

The proposed algorithm combines variational scheduling with post-processing to achieve near-optimal solutions to combinatorial optimization problems with constraints within the operation time of ...