Through x-ray crystallography and kinase-inhibitor specificity profiling, University of California San Diego School of Medicine researchers, in collaboration with researchers at Peking University and ...
Kyoto, Japan -- Curcumin, a natural molecule related to turmeric, has been used to treat cancer patients in cancer clinical studies. While it has documented antitumor effects, challenges involving its ...
A prodrug form of curcumin, TBP1901, has shown anti-tumor effects without toxicities. The enzyme GUSB was identified for its key role in TBP1901 conversion to curcumin, which also has essential ...
The high conversion rate of curcumin prodrug TBP1901 to curcumin in bone marrow warrants its clinical application for diseases growing in the marrow like multiple myeloma and leukemia. The natural ...
Though they are often used interchangeably, turmeric and curcumin are not the same. Turmeric is a flavorful spice from the ginger family, while curcumin is its most active compound known for powerful ...