(A) C3H10T1/2 cells were transfected with AdGFP, AdBMP2, AdDnNotch1, and AdBMP2+DnNotch1, respectively. On day 7, quantitative reverse transcription PCR was used to detect the expression of ...
A new study assesses the effect of the gremlin-1 (GREM1) protein on the in vitro and in vivo stability of bone marrow stem cell (BMSC)-derived cartilage engineered within scaffolds. The study design ...
Researchers have designed a novel, hybrid hydrogel system to help address some of the challenges in repairing bone in the event of injury. A team of UConn Health researchers has designed a novel, ...
Accumulating in vitro evidence suggests that the p38 mitogenactivated protein kinase (MAPK) pathway is involved in endochondral ossification. To investigate the role of this pathway in endochondral ...
Osteoblasts are the cells required for bone synthesis and mineralization, both during the initial formation of bone and during bone remodelling. These cells are present on the bone surface in the form ...
Joohyun Lim, Caressa Lietman, Matthew W. Grol, Alexis Castellon, Brian Dawson, Mary Adeyeye, Jyoti Rai, MaryAnn Weis, Douglas R. Keene, Ronen Schweitzer, Dongsu Park ...
A team of UConn Health researchers has designed a novel, hybrid hydrogel system to help address some of the challenges in repairing bone in the event of injury. The UConn Health team, led by associate ...