The fibrous proteins and ground substance produced by fibroblasts are what constitute the extracellular matrix (ECM), which makes up the bulk of connective tissue. The ECM has many roles within ...

University researchers have developed a new connective tissue model to study disorders like fibrosis, a type of scarring that occurs when damage to the body causes normal tissue to be replaced by hard ...

Abnormal scarring is a serious threat resulting in non-healing chronic wounds or fibrosis. Scars form when fibroblasts, a type of cell of connective tissue, reach wounded skin and deposit plugs of ...

Fibroblasts are the most common connective tissue cells. They produce the structural framework for animal tissues, synthesize the extracellular matrix and collagen, and play a critical role in wound ...

The central nervous system (CNS) consists of several types of cells having varied specialized functions. While many of these cell types have been studied, fibroblast cells in the CNS remain ...

Helmholtz Munich researchers revealed a conserved differentiation process with clinical implications for injury repair, identifying a multipotent fibroblast progenitor in the fascia— the deepest ...

(Nanowerk News) Researchers at PSI and ETH Zurich have taken connective tissue cells that have been mechanically reprogrammed to resemble stem cells and transplanted them into damaged skin. In their ...

Why are pancreatic tumors so resistant to treatment? One reason is that the 'wound'-like tissue that surrounds the tumors, called stroma, is so dense, likely preventing cancer-killing drugs from ...

Tumours have developed many strategies and tricks to gain advantages in the body. Led by cell biology professor Sabine Werner, researchers at ETH Zurich have now discovered another surprising trick ...