Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D ...

Tricking cancer cells into self-destructing could reduce risk of recurrence and death in colon cancer by 50%. Results also ...

In a new study led by researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania (Penn Medicine) researchers defined key ...

Your silver strands might be doing more than showing your age, according to a new study out of the University of Tokyo.

Throughout life, our cells are constantly exposed to environmental and internal factors that can damage DNA. While such DNA ...

Single-cell analyses revealed molecular profiles that can distinguish PTSD from depression, potentially leading to better drugs for this psychiatric disorder. To test this hypothesis, Girgenti and his ...

The ability of immune cells—particularly CD8+ T cells—to launch a rapid burst of proliferation inside tumors is key to the ...