Adopting a Quality by Design (QbD) approach for wet granulation requires manufacturers to comprehend the correlation between process variables, such as powder characteristics and equipment ...

Granulation is a critical unit operation in pharmaceutical manufacturing, where fine powders are agglomerated into granules to improve flow properties, uniformity, and compaction performance. The ...

At the manufacturing level, pharmaceutical manufacturers are leveraging advanced technologies and automation to address challenges such as sample under fill and overfill, detect contaminants and other ...

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...

Twin-screw granulation process insight is growing as researchers employ new analytical technologies and investigate new ways to use the equipment. The range of applications for twin-screw extruders as ...

FDA researchers present case studies using soft sensors to predict critical quality attributes and monitor crystallinity and ...

Small molecules, tablets, capsules, soft gels, effervescence, gummies, and pills. These are all oral solid dosage (OSD) forms, a term that refers to a final drug product therapy that is ingested ...

The course enables attendees to apply the theory learnt in the taught sessions, and also to directly observe the effect of formulation on product properties, and relate the theory to the practice of ...

Evolving equipment designs meet the unique needs of continuous processing techniques. Continuous manufacturing (CM) has the potential to create higher quality drug substances and drug products, with ...