BARCELONA, Spain — In the treatment of primary Sjögren disease, the use of leflunomide (LEF) and hydroxychloroquine (HCQ) in combination was associated with a greater reduction in disease activity ...
The nonbiologic DMARD leflunomide was approved for use in the treatment of rheumatoid arthritis in 1998. After being in use for more than a decade, which has also seen the introduction of highly ...