Research at the University of Jyväskylä (Finland) reveals that autonomous parvoviruses, such as canine parvovirus, are highly capable of affecting the internal balance of the nucleolus. The results ...

The nucleolus—a conspicuous but obscure organelle within the cell nucleus—is normally too compact to be studied in detail. Researchers at Case Western Reserve University just learned how to simplify ...

The primary function of the nucleolus is as the site of ribosome-subunit biogenesis in eukaryotic cells. The initial ribosomal RNA (rRNA) precursor is transcribed by RNA polymerase I and is ...

An essential component of living cells, the nucleolus underwent a major evolutionary shift around 300m years ago. Scientists have solved an age-old mystery in biology by discovering a protein found in ...

Proteins are the infinitely varied chemicals that make cells work, and science has a pretty good idea how they are made. But a critical aspect underlying the machinery of protein manufacture has long ...

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were ...

The size of a cell's nucleolus may reveal how long that cell, or even the organism it belongs to, will live. Over the past few years, researchers have been piecing together an unexpected link between ...

Biologists discovered that a scaffolding protein called TCOF1 is responsible for the formation of a biomolecular condensate called the fibrillar center, which forms within the cell nucleolus. Inside ...

In a recent study published in the Proceedings of the National Academy of Sciences (PNAS), researchers at the Texas A&M University Health Science Center (Texas A&M Health) identify a novel RNA ...