Over the past decade, there has been a significant decrease in the rate that new drug candidates are being translated into effective therapies in the clinic. In particular, there has been a worrying ...

What are the effects of all the medical drugs in our bodies? Pharmacology and Therapeutics in its entirety, embraces knowledge of the sources, chemical properties, biological effects and therapeutic ...

A recent US Food and Drug Administration (FDA) advisory committee meeting highlighted the potential of clinical pharmacology to overcome challenges in orphan drug development. There has been marked ...

The guidance document discusses the impact of clinical pharmacology considerations on peptide drug development. FDA published draft guidance on Dec. 13, 2023 that provides recommendations for the ...

In medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are discovered and/or designed. In the past most drugs have been discovered either by identifying the active ...

Metabolomics is the holistic study of metabolism. The application of metabolomics in pharmacology gives rise to a new field called “pharmacometabolomics.” The basic tenet of pharmacometabolomics is to ...

Current Molecular Pharmacology (CMP), a peer-reviewed international journal dedicated to publishing cutting-edge advances in cellular and molecular pharmacology, is proud to announce a major ...

With more than 120 researchers representing more than 16 countries around the world, and disciplines ranging from biomedical engineering to medicinal chemistry to fluorescence-guided surgery, our ...

Abtract"ECSTASY" (MDMA) AND RELATED DRUGS ARE AMPHETAMINE DERIVATIVES that also have some of the pharmacological properties of mescaline. They have become popular with participants in "raves," because ...