One of the greatest mysteries of our planet is how a soup of lifeless chemicals transformed into the first living cell. There are several competing theories about where this happened, from frozen ...

Researchers at the MRC Laboratory of Molecular Biology in Cambridge have discovered a ribozyme that is shockingly small, yet capable of the fundamental steps of self-replication. They call it QT45 — ...

Another factor related to their length is that they tend to form very complex structures, with many different areas of the ...

Premature termination of transcription influences ribosomal RNA output and RNA polymerase I drug sensitivity, revealing a mechanism of resistance to transcription-targeting chemotherapy.

AI can help protein engineers optimize the transcription enzymes used to make mRNA-based vaccines and therapeutics, say the authors of a new study.

From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine. But as ...

The discovery of catalytic RNA transformed our understanding of life's beginnings. Clare Sansom explores how the RNA world ...

Researchers developed C28, an engineered polymerase that efficiently synthesizes RNA at near-natural speeds with high accuracy. Created through directed evolution, the enzyme also performs reverse ...

IOCB Prague researchers showed that dinucleoside polyphosphates, known as alarmones, can initiate RNA transcription and form ...

Scientists have found a new process that happens when an active gene is transcribed from DNA into messenger RNA.. | Cell And ...