Premature termination of transcription influences ribosomal RNA output and RNA polymerase I drug sensitivity, revealing a mechanism of resistance to transcription-targeting chemotherapy.
Ribosomal subunit assembly and biogenesis constitute a fundamental process vital for cellular protein synthesis across all domains of life. This complex, multi-step pathway involves the transcription ...
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First-ever ribosomal synthesis of cyclic peptides opens new avenues for next-generation drug design
Inside our cells, ribosomes—the tireless "protein factories" of life—have just shown off a new skill they haven't used in billions of years. A research team has become the first in the world to ...
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