Conflicting findings are often reported in microbiome association studies, which could be due to insufficient sample sizes and numerous confounders. A new study, utilizing two large-scale human ...

Low statistical power undermines the purpose of scientific research; it reduces the chance of detecting a true effect. Perhaps less intuitively, low power also reduces the likelihood that a ...

Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations—CONCORDE BayeSize applies the concept of effect size ...

In the first part of this piece I pointed out why it can be difficult to validate TAR using control set metrics. When the overall proportion of responsive documents is very low, it becomes ...