P-cadherin is a protein commonly found on malignant cancer cells and has been used as a target for antibody-based cancer treatments. UC Davis biomedical engineers have discovered that when an antibody ...

Ten years of substantial work by Université de Montréal immunologist Nathalie Labrecque's team at the Montreal Clinical Research Institute (IRCM) and the Maisonneuve-Rosemont Hospital Research Center ...

A new study has found that MET (hepatocyte growth factor receptor) signaling plays a critical protective role in acetaminophen-induced acute liver failure (ALF). This pathway is shown to work as a ...

Australian researchers have uncovered a crucial new mechanism that helps explain how the heart's major blood vessels form ...

In a major brain science breakthrough, New Orleans-based researchers and collaborators have discovered a nerve signaling mechanism that takes place outside the cell, flipping on a 'pain switch.' This ...

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are essential for a wide range of cellular functions—as enzymes, transporters, ...

Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead ...

Plants mobilize their immune defenses far earlier than scientists have believed for decades—and through a previously overlooked early signaling mechanism—according to a new study published in Nature ...

A new method exposes key details of the mechanism behind calcium signaling in prokaryotes for the first time. Working in a Listeria monocytogenes model, researchers from Umeå University (Sweden) led ...

Cellular differentiation of stem cells into specialized cells requires many steps, including division, to create more cells; fate determination, which is a commitment to a specific lineage or ...