The SC3 tool was then used to analyse single-cell RNA-sequence data from two patients diagnosed with myeloproliferative neoplasm (MPN) blood cancers. Pre-malignant MPN occurs when the bone marrow ...

Researchers have created a comprehensive single-cell atlas of the human breast, which uncovers diverse cell types linked to ...

Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not well understood. In a new study published in Cell Genomics, researchers at ...

Tumor-wide RNA splicing aberrations and their potential as therapeutic neoantigen targets. Phase 1/2, open-label, first-in-human study of the anti-GPC3 T-cell engager SAR444200 in patients with ...

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

Singleron Biotechnologies today announced the launch of MobiuSCOPE, a single cell RNA sequencing kit that provides full-length transcript analysis using standard short-read sequencing. This solution ...

Single-cell RNA-seq (scRNA-seq) has spent the past decade maturing into a foundational technology. Over that time, the technology has both laid the foundation for building cell atlases and allowed ...

Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...