Researchers at The Wistar Institute's HIV Cure and Viral Diseases Center have successfully identified a new approach using ...

promoting antitumor activity and expansion of memory T cell precursors. HIV infection persists under antiretroviral therapy due to a reservoir of latently infected cells. This Perspective ...

Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its ...

HIV gradually weakens the body’s immune system by infecting and destroying white blood cells called T-cells. If left untreated, HIV causes AIDS – a life-threatening syndrome resulting from the ...

A mouse study at Memorial Sloan Kettering Cancer Center has found that adding Nef, a protein from HIV, allows donor CAR T cells to avoid detection by the immune system while still attacking tumors.

Human immunodeficiency virus type 1 (HIV-1) targets important cells of our immune system, making infected individuals more vulnerable to diseases and infections. Once inside human cells ...

A new advance may make it possible to use off-the-shelf CAR T cells provided by healthy donors. The new approach studied in mice equipped CAR T cells with the viral protein Nef.

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2024 — An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new study. By targeting infected cells in the brain ...