This image illustrates the process of gene transcription within a cell. The DNA double helix unwinds to expose a specific sequence, allowing RNA polymerase to synthesize a complementary pre-mRNA ...

Transcription-coupled DNA damage repair represents a specialised branch of nucleotide excision repair that ensures rapid removal of lesions from the transcribed strand of active genes. When RNA ...

An international research team led by Forschungszentrum Jülich and the IPK Leibniz Institute has developed an artificial ...

A new technology allows scientists to map, in single cells, the DNA binding sites of transcription factors and other regulatory proteins that control gene activity, according to a study led by ...

Transcription dynamics in the context of DNA damage response encompass the interactions between RNA polymerases and lesions within the DNA template, the resulting impact on transcriptional continuity, ...

Our genetic heritage is not a blueprint or an algorithm, as many biologists have imagined, but something else entirely.

While scientists have studied the molecular steps involved in gene expression for decades, many questions still remain about this fundamental process. To transcribe genes, RNA polymerase II (RNA Pol ...

D&D‑seq uses base editing to record DNA–protein interactions in single cells, enabling multiomics mapping of transcription ...

June 2026An international research team led by Forschungszentrum Jülich and the IPK Leibniz Institute has developed an ...

Researchers discover that the GPR3 receptor acts as an immediate-early gene to jumpstart neuron and synapse development.