Background Antimicrobial resistance (AMR) is a global threat for people with chronic lung infection; however, international AMR epidemiology in bronchiectasis and cystic fibrosis (CF) is poorly ...
Background Pulmonary rehabilitation (PR) is the cornerstone of non-pharmacological treatment for chronic obstructive pulmonary disease (COPD), yet fatigue often persists despite rehabilitation. We ...
Macrolide therapy is an established and effective treatment for selected patients with chronic obstructive airways diseases who experience frequent exacerbations despite optimal therapy. Randomised ...
Background: There is a growing recognition that genetic predisposition contributes to the development of fibrotic interstitial lung disease. Adult onset monogenic disease is most commonly due to ...
Coordinated bronchial, vascular and lobation abnormalities associated with right upper lobe agenesis
An 81-year-old woman with a history of diabetes mellitus and angina underwent chest CT after an abnormal chest radiograph suggesting a right pulmonary vascular abnormality. She had no respiratory ...
A 71-year-old man was admitted with presumed pneumonia. He was previously independent, had never smoked and had no history of domestic, environmental or occupational exposures. In the 2 years ...
Background Emerging evidence suggests that lung function decline may be linked to cardiovascular disease (CVD), but this has not been synthesised to date. This review aims to synthesise the current ...
Small-molecule oral Janus kinase (JAK) inhibitors are increasingly used for treatment of digestive and rheumatic inflammatory ...
Background International asthma guidelines recommend against epinephrine (adrenaline) administration in acute asthma unless associated with anaphylaxis or angio-oedema. However, administration of ...
2 Guy’s, King’s and St Thomas’ School of Medicine, London, UK 3 Department of Psychology, St George’s Hospital Medical School, London, UK 4 Pharmacia Consumer Healthcare, Medical Affairs, Helsingborg, ...
Background We performed an analysis of UK respiratory disease epidemiology covering 2004–2012. Findings pertaining to COPD are presented here. Methods Prevalence and incidence rates were estimated ...
Background Idiopathic pulmonary fibrosis (IPF) is a severe lung disease characterised by extensive pathological changes. The objective for this study was to identify the gene network and regulators ...
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