Despite notable advancements in the acute and long-term management, coronary artery disease and myocardial infarction (MI) ...

Though neither a physiologist nor a physician, William Shakespeare, a master observer, deftly noted the central roles of the ...

BACKGROUND: Evidence of the diverse genetic architecture of dilated cardiomyopathy (DCM) continues to emerge and requires ...

My experiences reflect knowing a community from the inside rather than judging it from the outside. Detroit was often depicted as lacking promise, but those within it recognized strengths that made ...

BACKGROUND: Cardiac troponin is increasingly used for cardiovascular risk prediction. While abnormal values often reflect ...

The adult mammalian heart is composed of many cell types, the most abundant being cardiomyocytes, fibroblasts, endothelial cells (ECs), and perivascular cells. Cardiomyocytes occupy ≈70% to 85% of the ...

Most composite end points for trials of a drug or device use a time-to-event or repeated-events approach for 2 clinically relevant outcomes (ie, death or hospitalization) that are assessed over the ...

All living organisms on Earth demonstrate rhythms in biological function, which are approximately tied to the 24-hour cycle of a single day and night. The term diurnal is commonly used to describe ...

Most physicians in the 1920s were general practitioners with relatively little postgraduate training. Although they measured blood pressure routinely, electrocardiograms and chest X-rays were in the ...

AVNRT is the most common regular supraventricular tachycardia. Catheter-based SP modification has become a first line treatment strategy with high success rates. Successful ablation can be judged ...

Branded medications dominated the prescription market in the 1980s, constituting 81% of fills in the United States. A majority lacked generic equivalents even after patent expiry. In 1984, the ...

In 2017, the American Academy of Pediatrics issued a new clinical practice guideline for defining hypertension in children as an update to the previous Fourth Report guidelines issued in 2004.