EurekAlert!

Revealing an invisible kinase state that accounts for vital biological function

(MEMPHIS, Tenn. – December 18, 2025) Scientists at St. Jude Children’s Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows ...
News Medical

KiNet web portal enhances study of kinase functions in cellular signaling pathways

Researchers from the Icahn School of Medicine at Mount Sinai have introduced KiNet, an interactive web portal designed to explore kinase-substrate interactions in human cellular systems. These ...
EurekAlert!

Mount Sinai researchers introduce web portal empowering drug discovery and systems-level analysis of critical kinase-substrate interactions

New York City (Oct 3, 2024) - Researchers from the Icahn School of Medicine at Mount Sinai have introduced KiNet, an interactive web portal designed to explore kinase-substrate interactions in human ...
Phys.org

Kinase enzymes exist throughout tree of life—those found in bacteria may be vulnerable targets for new antibiotics

Enzymes known as kinases play a critical role in cell growth, metabolism and signaling in a multitude of organisms across the tree of life—from algae to helminths to mammals. Now, scientists have ...
The Conversation

‘Pac‑Man with a ponytail’ proteins regulate everything from night vision to heartbeats – studying what GRKs look like could improve an array of drugs

Each cell in your body relies on precise communication with other cells to function properly. At the center of this process are the molecular switches that turn communication signals in the body on ...

Revealing the unusual ability of a protein involved in lung and thyroid cancer

Research conducted at the National Cancer Research Centre (CNIO) has revealed an unexpected behavior observed in a protein ...