The human P2X4 receptor plays an important role in chronic pain, inflammation and some types of cancer. Researchers at the ...

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur ...

Isomeranzin (ISM) binds to Gnas, activating adenylyl cyclase and elevating intracellular cAMP levels. This activation ...

Inhibitory receptors have increasingly been recognized as critical players in the maintenance of immune homeostasis. These receptors, expressed on a variety ...