Patrick Mahomes and Andy Reid lost 3 in a row to Lou Anarumo's Cincinnati defense. Can Anarumo bring that same unpredictability Sunday with Colts?

Minnesota's 2024 10th overall pick quarterback J.J. McCarthy is riding the struggle bus. He's registered a 52.9% completion percentage, eight total touchdowns and eight interceptions in five starts while throwing at least one interception in every start. He's also thrown for fewer than 200 yards in four of his five starts this season.

Kansas City Chiefs star quarterback Patrick Mahomes discusses sports gambling and how much attention he pays to it.

Patrick Mahomes and the Chiefs are struggling like we've never seen them struggle before during the QB's incredible career. After last Sunday's loss to the Broncos they sit out of the playoff picture at 5-5 and are set to host the red-hot 8-2 Colts this Sunday in a game that is feeling like a must-win situation for the three-time defending AFC champions.

Kansas City Chiefs QB Patrick Mahomes could join NFL legend Tom Brady as the only two players to accomplish a historic milestone.

If the Chiefs were 8-2, these would all be Champagne problems. At 5-5, they're concerning. But if KC misses the playoffs? The bubbly goes flat and all you're left with is an offseason of real problems.

Here is Cowherd's full take on Mahomes and the Chiefs:

We'll go over our favorite anytime touchdown scorer bets for Colts vs. Chiefs with odds from DraftKings Sportsbook. For a full game forecast for Colts vs. Chiefs and NFL player prop recommendations, check out the SportsLine Projection Model.