These mechanisms are kidney filtration, which can be slowed by increasing the size of a protein by adding N-glycan sites (Section 2.1.1) and avoiding receptor-mediated clearance by the ...

MIT neuroscientists have made a breakthrough in treating fragile X syndrome by leveraging a novel neurotransmitter signaling ...

Authors show that CD206-targeted antigens access both exogenous and cross-presentation pathways ... the interpretation of these data. Mannose receptors in both murine and human systems bind ...

This valuable work presents how PRDM16 plays a critical role during colloid plexus development, through regulating BMP signaling. Solid evidence supports the context-dependent gene regulatory ...

In a surprising discovery, scientists have found that the heart possesses "sweet taste" receptors, similar to those on our tongues, and that stimulating these receptors with sweet substances can ...

Joint injury induces rapid and sustained diversification of resident and infiltrating synovial macrophage phenotypes, underpinning osteoarthritis-associated synovitis.

A new study, "Identifying Allosteric Hotspots in Mycobacterium tuberculosis cAMP Receptor Protein" published in Biochemistry, provides key insights into how bacterial cAMP receptor proteins (CRPs) ...

2007 Future Drugs Ltd. Cite this: Human Mannose Receptor (CD206 ... can access both MHC class II and cross-presentation pathways in vivo and thus involve both humoral and cellular arms of immune ...

Who hasn't been there? The big meal is over, you're full, but the craving for sweets remains. Researchers from the Max Planck ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study. Blocking ...