ascopubs.org

Multimodal artificial intelligence (MMAI) model to identify benefit from 2nd-generation androgen receptor pathway inhibitors (ARPI) in high-risk non-metastatic prostate cancer ...

Phase 3, randomized, placebo-controlled clinical trial of CAN-2409+prodrug in combination with standard of care external beam radiation (EBRT) for newly diagnosed localized prostate cancer. Prognostic ...
ascopubs.org

Inverse Relation Between Responses to Pembrolizumab Plus Chemotherapy and Subsequent Cetuximab Plus Paclitaxel in Head and Neck Cancer: Role of the Janus Kinase–Signal ...

Pertuzumab and Trastuzumab in Patients With ERBB2/3-Altered Urothelial or Ovary/Fallopian Tube Cancer: Results From the Targeted Agent and Profiling Utilization Registry Study This study included 30 ...
PNAS

Failure of early B cell tolerance and possible BCR signaling dysregulation underlie NF155-mediated autoimmune nodopathies

We acknowledge the support of the patients and the assistance of Guilin Wang, Arun Chavan, the Yale Center of Genomic Analysis, and Beata Filipek. This research was supported by the NIH award ...
Phys.org

How a hidden receptor switch could open new paths for cancer and neurological treatments

A research team at Leipzig University has identified a mechanism in adhesion G protein-coupled receptors (adhesion GPCRs), a specific group of membrane receptors. This mechanism is essential for the ...