Researchers at The Wistar Institute's HIV Cure and Viral Diseases Center have successfully identified a new approach using ...

promoting antitumor activity and expansion of memory T cell precursors. HIV infection persists under antiretroviral therapy due to a reservoir of latently infected cells. This Perspective ...

This study provides evidence that single-cell multi-omics profiling can reveal key regulators of HIV-1 persistence and early immune dysregulation, particularly implicating KLF2 and Th17 cells as major ...

Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its ...

Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells) go through a surprising transformation -- and relocation -- as they fight infections in the small intestine.

A mouse study at Memorial Sloan Kettering Cancer Center has found that adding Nef, a protein from HIV, allows donor CAR T cells to avoid detection by the immune system while still attacking tumors.

we haven't got a solution to the problem yet," he said. An HIV infection is so difficult to cure because the virus is incredibly effective at hiding in our cells. When HIV infects our bodies ...

2024 — An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new study. By targeting infected cells in the brain ...

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By combining the Gaiha Lab's expertise in T cell immunology with the Barzilay ... The tool was validated using experimental data from influenza, HIV, and Epstein-Barr virus (EBV) and was able ...