openheart.bmj

Open Heart

is an open access journal by BMJ and BCS, publishing original research in cardiovascular medicine. Open Heart considers submissions of a variety of article types, including original research articles, ...
Open Heart

Maternal cardiac risk stratification in contemporary practice: external validation of mWHO, CARPREG II and ZAHARA in a 14-year tertiary cohort

Background Pregnancy in women with cardiac disease carries substantial maternal risk. The modified WHO classification, Cardiac Disease in Pregnancy Study II (CARPREG II) and Zwangerschap bij ...
Open Heart

Prevalence of aortic findings among patients with multifocal fibromuscular dysplasia (FMD) seen at a specialised referral centre

Background Fibromuscular dysplasia (FMD) is a non-atherosclerotic vascular disease that affects medium-sized arteries with multifocal (beaded) or focal stenotic lesions, aneurysms, dissections and ...
Open Heart

Association between delayed transcatheter aortic valve replacement beyond 6 months and clinical outcomes in severe aortic stenosis: a retrospective observationa…

Objective Early intervention for asymptomatic severe aortic stenosis (AS) has shown prognostic benefits; however, some ...
openheart.bmj

Walking a tightrope: the safety and efficacy of oral anticoagulants in atrial fibrillation patients with prior intracranial haemorrhage: a systematic review and meta-analysis

Introduction The optimal anticoagulation strategy for patients with atrial fibrillation (AF) and prior intracranial haemorrhage (ICH) remains uncertain. Although direct oral anticoagulants (DOACs) ...
openheart.bmj

Factors associated with length of stay among patients with acute myocardial infarction undergoing percutaneous coronary intervention: findings from the CCC-ACS project

Objective Prolonged length of stay (LOS) contributes substantially to the healthcare burden in patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI), yet ...
openheart.bmj

Validity, reliability and clinical utility of the Glittre ADL test in patients with atrial fibrillation

Background Activities of daily living (ADL) are frequently impaired in patients with atrial fibrillation (AF). Although the 6-Minute Walk Test (6MWT) is widely used for functional assessment, it ...
openheart.bmj

Explainable machine-learning model for coronary artery disease diagnosis in non-AMI patients: integrating inflammatory and traditional risk factors

Objective To develop and interpret an explainable machine learning (ML) model integrating inflammatory biomarkers and traditional risk factors for the diagnosis of coronary artery disease (CAD).
openheart.bmj

Non-invasive endotyping improves treatment satisfaction and prescribing appropriateness in patients with angina and no obstructive coronary artery disease

Background Patients with angina and no obstructive coronary artery disease (ANOCA) frequently receive empirical antianginal therapy that fails to target underlying pathophysiological mechanisms.
openheart.bmj

ST-segment elevation in acute pericarditis and myocardial involvement: electrocardiographic and clinical profiling

Background Pericardium is considered electrically inert, but diffuse ST-elevation is an electrocardiographic marker of acute pericarditis. We hypothesised that ST-elevation in acute pericarditis may ...
openheart.bmj

Long-term incidence of atrial fibrillation and cardiovascular outcomes in men and women with sinus rhythm: a 20-year follow-up of the INTERGENE population-based cohort

Background Estimates of long-term atrial fibrillation (AF) incidence in individuals with sinus rhythm are limited. This study investigated age-stratified and sex-stratified long-term incidence of AF ...
openheart.bmj

Table of contents

APCU25CR28 Navigating dual diagnosis: case report of amyloid transthyretin (ATTR) cardiac amyloidosis and amyloid light-chain (AL) (13 February, 2026) ...