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Learn more about Bing search results hereAntibody-drug conjugate medicationOrganizing and summarizing search results for youBrentuximab vedotin (brand name Adcetris) is an antibody-drug conjugate medication used to treat relapsed or refractory Hodgkin lymphoma (HL) and systemic anaplastic large cell lymphoma (ALCL). It combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). The drug is administered through infusion into a vein once every 2 or 3 weeks. It works by causing the immune system to attack lymphoma cells with the CD30 protein and disrupting functions critical to cell growth.4 Sources
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See all on WikipediaBrentuximab vedotin - Wikipedia
Brentuximab vedotin, sold under the brand name Adcetris, is an antibody-drug conjugate medication used to treat relapsed or refractory Hodgkin lymphoma (HL) and systemic anaplastic large cell lymphoma (ALCL), a type of T cell non-Hodgkin lymphoma. It selectively targets tumor cells expressing the CD30 … See more
Brentuximab vedotin was studied as monotherapy in 160 patients in two phase II trials. Across both trials, the most common adverse reactions (≥20%), regardless of … See more
Clinical trials
In a 2010, clinical trial, 34% of patients with refractory Hodgkin lymphoma achieved complete remission and another 40% had partial remission. Tumor reductions were achieved in 94% of patients. In ALCL, … See moreBrentuximab vedotin consists of the chimeric monoclonal antibody brentuximab (cAC10, which targets the cell-membrane protein See more
Legal status
In August 2011, the US Food and Drug Administration (FDA) granted accelerated approval to the biologics license application (BLA) … See moreWikipedia text under CC-BY-SA license ADCETRIS® (brentuximab vedotin) Classical Hodgkin Lymphoma …
ADCETRIS is a prescription medicine directed against the CD30 protein. It is used to treat: Adults with previously untreated Stage 3 or 4 classical Hodgkin lymphoma, in combination with …
ADCETRIS is indicated for the treatment of adult patients with previously untreated sALCL or other CD30-expressing PTCL, including angioimmunoblastic T-cell lymphoma and PTCL not …
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ADCETRIS® (brentuximab vedotin) | Official Patient …
ADCETRIS is a prescription medicine directed against the CD30 protein. It is used to treat: Adults with previously untreated Stage 3 or 4 classical Hodgkin lymphoma, in combination with chemotherapy (Adriamycin, vinblastine, and …
Brentuximab Vedotin (Adcetris) - NCBI Bookshelf
We provide Canada’s health system leaders with independent evidence and advice so they can make informed drug, health technology, and health system decisions, and we collaborate with …
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ADCETRIS® for Select Peripheral T-Cell Lymphomas
ADCETRIS® (brentuximab vedotin) treatment information for adults with certain untreated CD30-expressing peripheral T-cell lymphomas. See Safety info.
ADCETRIS® (brentuximab vedotin) HCP Home Page - Safety Info
Discover ADCETRIS® (brentuximab vedotin), a CD30-directed treatment for certain lymphomas. See full Prescribing Information, including BOXED WARNING.
ADCETRIS® (brentuximab vedotin) Patient information …
ADCETRIS is a CD30-directed antibody and microtubule inhibitor conjugate indicated for treatment of: Adult patients with previously untreated Stage III or IV classical Hodgkin lymphoma (cHL), in combination with doxorubicin, …
Adcetris Combo Approved for Rel/Ref Large B-Cell Lymphoma
2 days ago · Cancer Therapy Advisor offers the latest cancer management and treatment info, cancer research news, and more for oncologists and medical professionals.
U.S. FDA Approves Pfizer’s ADCETRIS® Combination …
3 days ago · NEW YORK--(BUSINESS WIRE)-- Pfizer Inc. (NYSE: PFE) announced today that the U.S. Food and Drug Administration (FDA) has approved the supplemental Biologics License Application (sBLA) for …
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