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Hemolytic anemia 1. Onset and Course Sudden onset of pallor and jaundice — especially after infection, fever, or drug intake. Dark urine appearing soon after fever or stress → suggests intravascular hemolysis. Recurrent episodes since infancy or family history → points to hereditary causes (e.g., G6PD deficiency, spherocytosis). 2. General Appearance Pallor (especially conjunctiva, palms) Icterus (yellow sclera/skin) — appears early and disproportionate to anemia. Lemon-yellow complexion (pallor
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