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John MacArthur taught that the Antichrist will arise from Islam. That claim may sound compelling in a post-9/11 world, but biblically and historically, it collapses under scrutiny. Islam did not arise out of the Roman Church, does not sit in the temple of God claiming divine authority, does not change God’s law, and does not fulfill the prophetic markers laid out in Daniel 7, Daniel 8, 2 Thessalonians 2, or Revelation 13. The Antichrist power is not merely hostile to Christianity—it claims to be