Rose Apple on Instagram: "💐Polycythemia Vera (PV) 💐 💐 type of Myeloproliferative Neoplasm (MPN) characterized by an abnormal increase in red blood cell production in the bone marrow. It is primarily caused by a JAK2 mutation (most commonly V617F), which makes hematopoietic cells overly sensitive to erythropoietin (EPO), leading to increased RBC production even when EPO levels are low. 💐Pathophysiology 🔸JAK2 V617F mutation is present in approximately 95% of cases. 🔸Another 2–3% carry JAK2 e
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Rose Apple on Instagram: "💐Polycythemia Vera (PV) 💐 💐 type of …
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